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Heralded by the formal inception of an Orthopaedic Resaech Group for the study of human bone and joints, experimental orthopaedic research was begun in 1979 at the University of Aarhus, Denmark. The group was designed to promote active, multidisciplinary cooporation among orthopaedic surgeons, engineers, pathologists, mathmaticians, rheumatologists and radiologists.

The three principal aims of this research group were to advance understanding of the pathophysiology of the arthritic joint, the physical properties of both healthy and degenerated cancellous bone, and the nature of different types of joint instability.

The size of the research corps increased gradually as did the number of research objectives. Research topics such as spinal hemodynamics, bone in-growth, bone interplants and bone induction are examples of such expansion.

Research has to a large extent been closely related to the clinical work of the Orthopeadic Department at the University Hospital of Aarhus. The close connection between research and clinical work has encouraged a high level of scientific activity and as such considered a creative success.


Erythropoietin augments bone formation in a rabbit posterolateral spinal fusion model.
Rölfing JHD, Bendtsen M, Jensen J, Stiehler M, Foldager CB, Hellfritzsch MB, Bünger C.
Phenol Red Inhibits Chondrogenic Differentiation and Affects Osteogenic Differentiation of Human Mesenchymal Stem Cells in Vitro.
Lysdahl H, Baatrup A, Nielsen AB, Foldager CB, Bünger C.
Navigated percutaneous lumbosacral interbody fusion: a feasibility study with three-dimensional surgical simulation and cadaveric experiment.
Wang Y, Le DQ, Li H, Wang M, Bünger CE.
Orthopaedic Spinal Research      Aarhus University Hospital      Noerrebrogade 44      Building 1A      8000 Aarhus C      Phone: +45 7846 4133
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