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Evaluation of Health Economics at the Orthopaedic Spinal Research Laboratory

Health ecomomic evaluation is a relatively new decipline within clinical orthopaedics which combines methodology from epidemiology, biostatistics/econometrics, and economics. In specific, the type of evaluation which is being conducted at the Orthopaedic Research Laboratory is stochastic cost-effectiveness analysis, that is, analysis based on randomised clinical trials.

The health economic research being undertaken is, to a large extent, based upon the availability of high-quality register data from national registries such as the National Patient Register, the National Health Insurence Service Register, Register of Prescribed Medication and the Social Science Research Register. The Orthopeadic Research Laboratory is authorised by Statistics Denmark to conduct register based research using these registries.

One important rationale for health economic evaluation is a political desire for allocative effeciency i.e. that society maximizes its health gain from the health care budgets available. Our research aims at informing national politics i.e. we compare alternative clinical regimes using generic outcome measures to provide a cost per quality-adjusted life year (QALY) to allow for prioritization across diseases and interventions, not necessarily limited to orthopeadics.


Current and planned projects

Following projects are being published - Evaluation of surgical techniques in DESE operations: 360° spondylodesis versus back DESE. The results are being presented at the ISLS in Hong Kong in June 2007. The project has received funds from Gigtforeningen. - Evaluation of rehabilitation after DESE operation; the hospital’s usual method versus a “Back Café” protocol versus intensive training therapy. The project has received funds from Gigtforeningen. - An observational study of determinants of the cost-effectiveness in lower-back surgery


Erythropoietin augments bone formation in a rabbit posterolateral spinal fusion model.
Rölfing JHD, Bendtsen M, Jensen J, Stiehler M, Foldager CB, Hellfritzsch MB, Bünger C.
Phenol Red Inhibits Chondrogenic Differentiation and Affects Osteogenic Differentiation of Human Mesenchymal Stem Cells in Vitro.
Lysdahl H, Baatrup A, Nielsen AB, Foldager CB, Bünger C.
Navigated percutaneous lumbosacral interbody fusion: a feasibility study with three-dimensional surgical simulation and cadaveric experiment.
Wang Y, Le DQ, Li H, Wang M, Bünger CE.
Orthopaedic Spinal Research      Aarhus University Hospital      Noerrebrogade 44      Building 1A      8000 Aarhus C      Phone: +45 7846 4133
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